Plantar fasciitis is a painful and debilitating condition that can, at times, be recalcitrant in nature and difficult to treat with conservative care. Understanding the pathophysiology of the condition is imperative for successful treatment. Front line treatment for years has included steroid injections of the heel as well as physical therapy, use of a night splint, modifications of shoe gear, and implementation of pre-fabricated and/or custom molded orthoses. This treatment plan targets the immediate pain secondary to inflammation as well as the underlying pathomechanics and deformities coupled with different foot types.
Other factors such as activity level also play a large role in the etiology, but are often most difficult to control. When conservative treatment measures have failed in the past, other treatments have been used such as Platelet-Rich Plasma (PRP) injections, Extracorporeal Shockwave, Topaz procedures or surgery with plantar fasciotomy ranging 
from open to percutaneous and even endoscopic procedures. However, recent use of a chorion-free, human-amnion allograft implant suggests that there is a non-surgical, clinically effective alternative to the aforementioned procedures. The implant by injection of a chorion-free, amnion-derived allograft appears to offer the clinician an additional treatment option when conservative measures have proven unsuccessful.
Amniotic fluid and membrane have been used to treat various medical conditions for over 100 years, including chronic wounds, inflammation, thermal injury and orthopedic defects. Its utility is derived from a tissue which is rich in mesenchymal cells, growth factors and anti-inflammatory proteins that support the body
